Science
Scientists Uncover 1 Million-Year-Old DNA in Woolly Mammoth Remains

Researchers have identified DNA dating back over one million years in the remains of woolly mammoths, marking a significant breakthrough in the study of ancient microbial life. An international team, led by scientists from the Centre for Palaeogenetics in Sweden, analyzed microbial DNA from 483 mammoth specimens, with 440 of those sequenced for the first time. Among these specimens was a steppe mammoth that lived approximately 1.1 million years ago.
Revolutionizing Microbial DNA Research
Using advanced genomic and bioinformatic techniques, the researchers successfully distinguished between microbes that coexisted with the mammoths and those that entered their remains post-mortem. Lead author, Dr. Benjamin Guinet, expressed excitement over the findings, stating, “Imagine holding a million-year-old mammoth tooth. What if I told you it still carries traces of the ancient microbes that lived together with this mammoth?”
The study identified six microbial groups consistently associated with mammoth hosts, including relatives of Streptococcus, Actinobacillus, Pasteurella, and Erysipelothrix. Some of these microbes may have been pathogenic; notably, one bacterium related to Pasteurella is closely linked to a pathogen responsible for fatal outbreaks in African elephants. This raises intriguing questions about whether woolly mammoths were susceptible to similar diseases.
Insights into Ancient Ecosystems
The team successfully reconstructed partial genomes of Erysipelothrix from the 1.1-million-year-old steppe mammoth, marking the discovery as the oldest known host-associated microbial DNA ever recovered. Senior author, Dr. Tom van der Valk, emphasized the significance of the findings, stating, “As microbes evolve fast, obtaining reliable DNA data across more than a million years was like following a trail that kept rewriting itself.” This research suggests that ancient remains can provide biological insights far beyond just the host genome, illuminating the complex interactions between ancient hosts and their microbiomes.
While determining the precise impact of the identified microbes on mammoth health poses challenges due to DNA degradation and limited comparative data, the study offers an unprecedented glimpse into the microbiomes of extinct species. Published in the journal Cell, the findings imply that certain microbial lineages coexisted with woolly mammoths for hundreds of thousands of years, traversing significant geographical ranges and evolutionary timelines. This extends from over one million years ago to the extinction of woolly mammoths on Wrangel Island approximately 4,000 years ago.
Professor Love Dalén, an ancient DNA expert at the Centre for Palaeogenetics, remarked on the groundbreaking nature of this research. “This work opens a new chapter in understanding the biology of extinct species. Not only can we study the genomes of mammoths themselves, but we can now begin to explore the microbial communities that lived inside them,” he stated.
The study not only expands our understanding of ancient ecosystems but also highlights the potential for future research into how microorganisms may have influenced adaptation, disease, and extinction in the Pleistocene epoch. The revelations from this research may pave the way for new insights into the lives of these fascinating creatures.
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