Science
Stunning Microscopic Images Challenge Perceptions of Reality

The annual Nikon Photomicrography Competition has revealed an astonishing array of microscopic images that challenge our understanding of the natural world. Among the notable entries, German chemical engineer Jan Rosenboom captured a striking photograph of a drop of water filled with tiny spheres of colonial algae, earning him the runner-up position in this prestigious event. This competition celebrates the art and science of microscopy, inviting professionals and enthusiasts alike to showcase their work.
Each year, the competition draws submissions from around the globe, featuring images that offer new perspectives on familiar objects. The 2025 winners include a range of subjects, from intricate human cellular structures to the hidden ecosystems within ordinary mushrooms. For a comprehensive look at the winners, the full list is available on Nikon’s official website.
Highlights from the Competition
Among the standout entries, Wim van Egmond from the Micropolitan Museum in the Netherlands secured ninth place with his stunning close-up of red pigments from the fungus Talaromyces purpureogenus. This fungus is a distant relative of the penicillin-producing Penicillium, showcasing the vibrant colors that can be found in the microscopic world.
Another impressive image came from researchers at the Friedrich Miescher Institute for Biomedical Research in Switzerland. They utilized confocal microscopy to capture a remarkable view of a mouse colon, a crucial subject in biomedical research. This technique highlights cells marked with fluorescent probes, providing deep insights into cellular functions.
Vanderbilt University’s James Hayes presented a captivating image of heart muscle cells, which displayed chromosomes condensing after cell division. These images underscore the dynamic processes occurring within our bodies, often unnoticed by the naked eye.
The competition also featured a striking photograph of iPSC-derived sensory neurons taken by Stella Whittaker from the National Institutes of Health (NIH). The image, resembling a swirling black hole, showcases the intricate structures of the neurons, labelled to highlight two essential proteins: tubulin and actin.
Nature’s Intricate Relationships
Some entries depicted the complex interactions within nature itself. Igor Robert Siwanowicz of the Howard Hughes Medical Institute captured a compelling image of marrow pollen germinating on stigma while being parasitized by a filamentous fungus. This photograph illustrates the often brutal realities of interdependence in the microscopic realm.
Another standout image, awarded third place, featured pollen spores suspended on a garden spider web. Captured by John-Oliver Dum from Germany’s Medienbunker Produktion, this photograph employed a technique that combined multiple shots to create a striking visual representation of nature’s delicate yet resilient structures.
The overall winner of the competition, Zhang You, an entomologist from China, presented an extraordinary image of a rice weevil in flight atop a grain of rice. This photograph is a composite of over 100 individual images, meticulously processed to enhance clarity and impact. In his statement, Zhang emphasized that this achievement is the culmination of years spent focusing on ecological and insect science photography.
These captivating images not only highlight the beauty of the microscopic world but also serve as a reminder of the complexities and interconnections within nature. As advancements in microscopy continue to unfold, the potential for discovering new insights into the natural world remains limitless.
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