Roswell Park Unveils Groundbreaking Lung Cancer Radiation Therapy

Experts from the Roswell Park Comprehensive Cancer Center will present innovative findings on a new radiation therapy protocol for lung cancer at the upcoming American Society for Radiation Oncology (ASTRO) Annual Meeting, scheduled for September 27 to October 1, 2025, in San Francisco, California. The research focuses on a novel approach to delivering a high dose of radiation therapy post-surgery for patients diagnosed with non-small cell lung cancer (NSCLC).

Dr. Mark Farrugia, a Clinical Assistant Professor of Oncology at Roswell Park, will deliver an oral abstract detailing a study that evaluates the feasibility and toxicity of this treatment method. The study, led by senior author Anurag Singh, Professor of Oncology and Director of Radiation Research at Roswell Park, has garnered significant attention and will also be highlighted during the ASTRO Science Highlights Session, which features top-rated abstracts.

Study Overview and Presentation Details

The clinical trial, classified as a single-arm prospective study, investigated the outcomes of administering a single fraction of stereotactic body radiation therapy to patients following surgery. The abstract for this research, titled “A Feasibility and Toxicity Analysis of Single-Fraction Stereotactic Body Radiation Therapy for Post-Operative Non-Small Cell Lung Cancer,” will be presented during the Science Highlights Session on September 28, 2025, from 8:00 to 8:30 a.m. PT in room 160. The oral presentation will take place the following day, September 29, 2025, from 5:40 to 5:50 p.m. PT in room 155/157.

In addition, two poster presentations from Roswell Park will take place on September 29, 2025, showcasing further advancements in cancer treatment. One of these posters, authored by Neil Almeida, a resident physician in the Department of Radiation Medicine, is titled “Early Initiation of Radiation Therapy Improves Survival in Elderly Patients with Glioblastoma” (Abstract 2558). This presentation is scheduled for 8:00 to 9:00 a.m. PT in Hall F, with Dr. Dheerendra Prasad, Chief of Gamma Knife Radiosurgery, serving as the senior author.

Significance of the Research

The findings presented at the ASTRO Annual Meeting could significantly impact treatment strategies for lung cancer patients. The innovative use of high-dose radiation therapy aims to improve patient outcomes and enhance the overall effectiveness of post-operative care.

Dr. Singh, the senior author for another relevant study, will discuss the “Association of Systemic Inflammation Response Index with Outcomes among Patients with Head and Neck Cancer Receiving Definitive Chemoradiation” (Abstract 2704). This poster is set for presentation on September 29, 2025, from 10:45 a.m. to noon PT in Hall F.

As the medical community gathers in San Francisco for this prominent event, the research from Roswell Park Comprehensive Cancer Center stands out as a promising development in the ongoing fight against cancer. The insights gained from these studies may pave the way for improved treatment protocols and better patient care in oncology.