Medical Experts Challenge Trump’s Claims Linking Tylenol to Autism

Major medical organizations have expressed strong concern following statements made by former President Donald Trump regarding the safety of acetaminophen, the active ingredient in Tylenol, during pregnancy. During a press conference on September 22, 2025, Trump announced that the Food and Drug Administration (FDA) would be advising doctors to limit the use of Tylenol by pregnant women unless absolutely necessary. He also indicated that the FDA would update the labeling for acetaminophen to include information about a potential link to autism.

The response from medical professionals was swift. Organizations such as the American College of Obstetricians and Gynecologists (ACOG) and the Society for Maternal-Fetal Medicine (SMFM) condemned the claims as “highly concerning” and “irresponsible.” They emphasized that over two decades of research have consistently shown no causal relationship between acetaminophen use during pregnancy and autism, attention-deficit/hyperactivity disorder, or intellectual disabilities.

Dr. Steven J. Fleischman, president of ACOG, articulated the essential role acetaminophen plays in managing pain and fever during pregnancy. He stated, “Maternal fever, headaches as an early sign of preeclampsia, and pain are all managed with the therapeutic use of acetaminophen, making acetaminophen essential to the people who need it.” The groups underscored that untreated fever and pain could pose far greater risks to both mothers and their unborn children.

The public health implications of untreated conditions during pregnancy were further highlighted by SMFM. They noted that untreated fever, particularly in the first trimester, can increase the risk of miscarriage, birth defects, and premature birth. Additionally, untreated pain may lead to maternal depression, anxiety, and high blood pressure.

During the same press conference, Trump and Robert F. Kennedy Jr., the Secretary of Health and Human Services, suggested that the childhood vaccination schedule might be linked to autism. This assertion stands in stark contrast to numerous studies over the years which have found no credible connection between vaccines and autism. In response, medical organizations reiterated the importance of vaccinations, stating, “Studies have repeatedly found no credible link between life-saving childhood vaccines and autism.”

The American Academy of Pediatrics (AAP) emphasized that vaccines do not overwhelm or weaken children’s immune systems. They argued that spacing out vaccinations may leave children vulnerable to serious, preventable diseases.

In a related development, the Trump administration announced the initiation of the approval process for a drug called leucovorin, which has shown early promise in treating autism symptoms in small studies. However, experts have cautioned that the evidence supporting these claims is limited and that many of the studies conducted are methodologically weak. The Coalition of Autism Scientists urged for more rigorous, large-scale trials before any clinical recommendations are made.

The Autism Society of America (ASA) condemned the administration’s promotion of “unfounded” claims regarding autism’s causes and treatments. They reiterated that autism is a complex condition with no single cause or cure. The ASA emphasized the importance of high-quality research and robust scientific evidence to guide treatment and support for the autism community.

In light of the administration’s statements, many in the medical community are advocating for increased investment in peer-reviewed autism research that includes independent oversight. They argue that the focus should remain on providing services and support to improve the quality of life for individuals with autism and their families.

The conflicting messages from the Trump administration have sparked concern among healthcare professionals and parents alike. Many are seeking clarity on the implications of these claims for public health and the well-being of children. The ongoing debate around acetaminophen, autism, and vaccinations underscores the critical need for science-based policy and communication in matters of public health.